EPS Extrapyramidal Syndrome

ANTIPSYCHOTIC-INDUCED MOVEMENT DISORDERS

·       Extrapyramidal Symptoms – EPS are caused by antipsychotic treatment and need to be monitored/evaluated for early intervention.

Akinesia – rigidity and bradykinesia

Akathisia – restlessness, movement of the body; unable to keep still; movement of feet

Dystonia – spasmodic and painful spasm of muscle (torticollis)

Oculogyric crisis – eyes roll back forward the head (emergency situation)

Pseudoparkinsonism – simulates Parkinson’s disease with shuffling gait, drooling, muscular rigidity and tremor

Rabbit Syndrome – rapid movement of the lips that simulates a rabbit mouth movement.

·       Tardive Dyskinesia – a permanent dysfunction of voluntary muscles. Affects the mouth – tongue protrudes, smacking of lips, mouth movements.

Biperidin hydrochloride ( Akiniton) – example of anti-EPS drug