Diagnostic Procedure
Alpha-fetoprotein ( AFP) that has leaked from the defect results in an elevated level in maternal blood in a specimen obtained at 16 to 18 weeks gestation. Amniocentesis detects the presence of AFP that has leaked into the amniotic fluid surrounding the fetus. The presence of spina bifida can be diagnosed prenatally ultrasound.
Fetal karyotyping detects chromosomal abnormalities.
Maternal serum AFP screening in combination with other serum markers.
Ultrasonography may detect an open NTD in utero on thebasis of family history or abnormal serum screening.
Spinal X-ray to identify spina bifida occulta.
Transluminationof the protruding sac
CT scan and X-rays show a basilar bony skull defect.
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